Chih-Yu Chao, Professor, Department of Physics & Institute of Applied Physics, National Taiwan University
200kV-FEG transmission electron microscope
Most biological mechanisms of living organisms are carried out through large molecular assemblies in the range of 10 to 100 nanometers. Cryo-electron microscopy(cryo-EM) provides architecture of these "molecular machines" and extends the capabilities of structural biology. We aim to understand the molecular structure of these macromolecules which is not only essential for the comprehension of their function and mechanism, but can also provide clues for the developing therapeutics related to health and disease.